The Incidence and Intensity of Postendodontic Pain and Flareup in Single and Multiple Visit Root Canal Treatments: A Systematic Review and Meta-Analysis

To assess the incidence and intensity of postendodontic pain flareup in single multiple visit root canal treatment (RCT) determine if difference between two is significant, a search PubMed, Medline, Embase, Cochrane, Scopus Web science was conducted. The grey literature searched using Google Scholar Saudi digital library. Randomised controlled trials evaluating published English from 1 January 2000 to 15 April 2020 were searched. PRISMA protocol followed select articles. A random effects model used for meta-analysis data included studies. Twenty-one articles review. Three compared both intensity, while rest either one parameters. Most studies hand-driven rotary instruments irrigated with sodium hypochlorite. Twelve an intracanal medicament. Although individual showed discordant outcomes, did not reveal any significant or RCT groups. Single independent determinant risk flareup.